12-letter words containing i, s, e, r, l, o
- whole sister — a sister whose parents are the same as one's own.
- wigglesworth — Michael, 1631–1705, U.S. theologian and author, born in England.
- world series — an annual series of games between the winning teams of the two major leagues: the first team to win four games being champions of the U.S.
- worldly-wise — wise as to the affairs of this world.
- wormseed oil — chenopodium oil.
- zillionaires — Plural form of zillionaire.