fugitive — a person who is fleeing, from prosecution, intolerable circumstances, etc.; a runaway: a fugitive from justice; a fugitive from a dictatorial regime.
out of hand — the terminal, prehensile part of the upper limb in humans and other primates, consisting of the wrist, metacarpal area, fingers, and thumb.
on the run — to go quickly by moving the legs more rapidly than at a walk and in such a manner that for an instant in each step all or both feet are off the ground.