aggravate — If someone or something aggravates a situation, they make it worse.
annoy — If someone or something annoys you, it makes you fairly angry and impatient.
disaffect — to alienate the affection, sympathy, or support of; make discontented or disloyal: The dictator's policies had soon disaffected the people.
irritate — to excite to impatience or anger; annoy.
anger — Anger is the strong emotion that you feel when you think that someone has behaved in an unfair, cruel, or unacceptable way.
bitter — In a bitter argument or conflict, people argue very angrily or fight very fiercely.
bother — If you do not bother to do something or if you do not bother with it, you do not do it, consider it, or use it because you think it is unnecessary or because you are too lazy.
venom — the poisonous fluid that some animals, as certain snakes and spiders, secrete and introduce into the bodies of their victims by biting, stinging, etc.