The bone marrow is also hypercellular with varying amounts of granulocytic and erythroid hyperplasia.
The cellular morphology suggested possible erythroid differentiation, however a hemoglobin peroxidase study was negative.
Severe anemia due to bone marrow aplasia is often a major complication as a result of viral replication in erythroid precursors.
Bone marrow biopsy and other hematologic tests were consistent with agranulocytosis and marked erythroid hypoplasia of the megakaryocyte type.
Sections of the bone marrow demonstrated areas of erythroid hyperplasia; however, there was no evidence of malignant lymphoid infiltrates or a significant increase in blast cells.
Megakaryocytes and erythroid precursors were not apparent, and no microorganisms were identified.
Pronounced erythroid hyper- piasia and a full range of myeloid maturation.
