It remains to be determined whether individual genes that contribute to MR in cases of aneuploidy or other chromosomal defects can mutate to an MR phenotype individually.
Recombinant gametes may have differential fitness due to aneuploidy or epistatic interactions.
Patients with aneuploid tumors have a poorer five-year survival rate than patients with diploid tumors.
DNA ploidy analysis on Feulgenstained sections indicated that the large cell region was composed of predominantly tetraploid and aneuploid cells.
Ten of 18 diploid neoplasms were associated with an adverse event, and 2 of 9 aneuploid neoplasms were associated with an adverse event.
Special schemes were not required to avoid aneuploidy of X chromosome segments because exchange occurred in heterochromatin.
The most direct way to assess chromosomal aneuploidy is to evaluate chromosome numbers in metaphase cells.
Genomic instability can take many forms, including aneuploidy and changes in chromosome structure.
