Also, hypochondriacal, H05/H0509000 hahy-poh-kuh n-drahy-uh-kuh l, ˌhaɪ poʊ kənˈdraɪ ə kəl. Psychiatry. pertaining to or suffering from hypochondria, an excessive preoccupation with and worry about one's health: The comedy is aimed at the hypochondriac demographic. produced by hypochondria: Hypochondriac feelings overwhelmed her.